Product ID:PENTHRANE,USP(NDC 74-6864-03)
MSDS Date:08/06/1985
FSC:6505
NIIN:01-134-3199
MSDS Number: BGNJM

ABBOTT LABORATORIES,HOSPITAL PRODUCTS DIV

ABBOTT PARK, DEPT 361 AP 6B
NORTH CHICAGO, IL 60064-3502
US

Emergency Phone: 312-937-6100

Info Phone: 312-937-6100

Cage: 60060

ABBOTT LABORATORIES INC

NORTH CHICAGO, IL 60064 US

Telephone: 847-935-7177

Cage: 60060

METHOXYFLURANE (PENTHRANE) USP

CAS: 76-38-0

RTECS: KN7820000

Fraction By Weight: >99%.

2,6-DI-TERT-BUTYL-P-CRESOL

CAS: 128-37-0

RTECS: GO7875000

Fraction By Weight: 0.01%

OSHA PEL 10 MG/M3

ACGIH TLV: 10 MG/M3; 9192

LD50 LC50 Mixture:ACUTE ORAL(2000-3600 MG/KG MOUSE,MAMMAL)
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Health Hazards Acute and Chronic:SYSTEMIC TOXICITY CAN RESULT FROM ORAL
INGEST. OR INHAL. RENAL & HEPATOXICITY HAVE BEEN REPORTED; REPORTED
TO BE CYTOTOXIC IN MUTAGENICITY TEST INVOLVING HUMAN LYMPHOCYTES.
TARGET ORGANS: LIVER, KIDNE Y, NERVOUS SYSTEM, REPRODUCTIVE, EYE;
SUBCHRONIC INHAL STUDIES(MONKEYS & RATS):FAT ACCUMUL. IN LIVER &
INCR. LVR. WGHT
Effects of Overexposure:EYES: IRRITANT(PRODUCES
REDNESS,SWELLING,CORNEAL CHANGES,IRIS CHANGES & DISCHARGE IN
RABBITS W/MOST IRRITAT. CLEARING IN 2-3 DAYS; SKIN: MODERATE
IRRITAT. TO RABBIT'S EAR; INHAL/INGEST: SYSTEMIC TOXIC ITY
W/EXCITEMENT,UNCONSCIOUSNESS & DEATHFROM RESPIRATORY COLLAPSE.

First Aid:REMOVE CONTAMINATED CLOTHING & WASH AFFECTED AREAS W/SOAP &
WATER. IF INHALED OR SWALLOWED, SEEK IMMEDIATE MEDICAL ATTN; IF
PATIENT IS UNCONSCIOUS, SUPPORT RESPIRATION, KEEP AIRWAY FREE OF
OBSTRUCTION .

Flash Point Method:CC
Flash Point:99F/37.2C
Extinguishing Media:"ALCOHOL" FOAM, DRY CHEMICAL, CARBON DIOXIDE
Fire Fighting Procedures:WEAR PROTECTIVE CLOTHING & SELF-CONTAINED
BREATHING APPARATUS.
Unusual Fire/Explosion Hazard:NOT DETERMINED

Spill Release Procedures:ABSORB INTO CLAY, SAND OR EARTH & PLACE INTO
APPROPRIATE CONTAINER; PREVENT SPILLAGE FROM DIRECTLY ENTERING
GROUND OR NAVIGABLE WATERS. WEAR APPROPRIATE PROTECTIVE CLOTHING
WHILE WORKING TO CONTAIN SP ILLAGE.

Handling and Storage Precautions:AVOID EXCESSIVE STORAGE TEMPERATURES &
DIRECT SUNLIGHT.

Respiratory Protection:FULL-FACE SUPPLIED AIR(AS REQUIRED)
Ventilation:LOCAL VENTILATION
Protective Gloves:HIGH DENSITY PLASTIC TYPE(SOLUBLE IN RBB
Eye Protection:CHEMICAL GOGGLES OR FACE SHIELD
Other Protective Equipment:AS REQUIRED FOR TASK AT HAND.
Work Hygienic Practices:READ MANUFACTURER'S PRODUCT LITERATURE &
INFORMATION IN PHYSICIANS DESK REFERENCE(PDR).
Supplemental Safety and Health
TERATOGENICITY: REPORTED IN RATS; DELAYS FETAL DEVELOPMENT IN RATS;
EMBRYOTOXIC IN RABBITS; ACUTE ORAL TOX(HUMAN FATAL DOSE 10 ML,
LD(LOW-MAN) 140 MG/KG); ACUTE INHAL TOX(TC(LOW-MAN) 3500 PPM/1 HR,
LC 50: 34-123 G/CUM RAT, MOUSE, MAMMAL)

HCC:F3
Boiling Pt:B.P. Text:221F/105C
Melt/Freeze Pt:M.P/F.P Text:-31F/-35C
Vapor Pres:22.5MM 68F
Vapor Density:4.7
Spec Gravity:1.38
Appearance and Odor:CLEAR, COLORLESS LIQUID WITH SWEET FRUITY ODOR
Percent Volatiles by Volume:99.09

Stability Indicator/Materials to Avoid:YES
POLYVINYL CHLORIDE PLASTICS, ACTS AS AN EXTRACTING AGENT;
TETRACYCLINES; QUITE SOLUBE IN RUBBER
Stability Condition to Avoid:HIGH TEMPERATURES; INTERACTION
W/TETRACYCLINES INCREASES RENAL TOXICITY.
Hazardous Decomposition Products:NOT DETERMINED

Waste Disposal Methods:INCINERATE IN AN APPROVED INCINERATOR OR TAKE TO
A CHEMICALLY SECURE LAND DISPOSAL SITE.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.